Ashwagandha has gained attention as a potential nutraceutical for supporting gastrointestinal health. This review examines its botanical profile, bioactive compounds and mechanisms tied to digestive function, including anti-inflammatory, antioxidant and immunomodulatory actions. Evidence from preclinical studies suggests benefits in ulcer protection, intestinal inflammation and motility regulation. Early clinical findings point to improvements in stress-related digestive symptoms and overall comfort, with a generally favorable safety profile. Despite promising results, research is limited by inconsistent extract quality and a lack of long-term clinical trials. Standardized formulations and targeted studies are needed to confirm Ashwagandha’s therapeutic role in gastrointestinal care.